All of the sudden Visual Studio 2010 decided to not work. The install was on a laptop I had not touched since I last did a presentation at a user group (about 2-3 weeks). I go to start it up to test out the code for my presentation (that night) and got a lovely error message when trying to start Visual Studio, “The operation could not be completed” and that was it.
I tried safe mode start-up “devenv.exe /safemode” and also removing all add-ins and extensions. I also tried resetting user settings “devenv.exe /resetsettings” and all the other switches I could find. Nothing. This was a random out of the blue problem.
I tried to install SP1 but got the same error which caused SP1 install to fail. I uninstalled all Visual Studio items and did a reinstall. Same problem.
Finally I found an MSDN post where the poster said he solved it by renaming “%ProgramFiles%\Common Files\Microsoft Shared\VS7DEBUG” to something else. I changed it to VS7DEBUG1.
After that, it started working just fine. What the original problem was, I have no idea.
Code Insights 
Skype recently had a similar situation with a few of its users. It wouldn’t launch unless you removed / renamed shared.xml.
Microsoft and Skype.. Together.. Similar issue.. Conspiracy? Just kidding of course.
had this same problem ‘Operation Could Not Be Completed’ … tried everything then came across this post http://tridentworkflow.codeplex.com/workitem/12491 that said to use mklink and that fixed the problem for me. Good luck.
I resolved the problem by simply doing a windows system restore! :)
I think its a problem with windows update as i just noticed some updates failed ill try installing them and post an update
i have installed the updates but its still not working i tried what you said renaming the folder
that did not work either
the folder rename method didn´t work for me too…
i am also facing same problem…rename method not Working
I’m also facing same problem…(after Windows update file “Microsoft .NET Framework 4 Client Profile for Windows 7 x86 (KB982670)” i’m using Windows 7)..
c:\Program Files\Common Files\microsoft shared\VS7DEBUG
change into
VS7DEBUG1
But this rename method is not working.. please give any other solutions.
Exact same problem with KB982670 Visual Studio 2010 will no longer start “This Operation Could Not Be Completed”
folder renaming technique isnt working for me too
try to install .NET Framework 4.5 http://www.microsoft.com/en-us/download/details.aspx?id=30653
in my case the *.vcxproj.filters file was read only and I wanted to add an existing file to the project, so removing the read only flag helped
Go to Run type “inetmgr” i.e IIS is open and on right corner Action window select option change “.Net Framework version ” change it After that reinstall your Visual studio 2010. it works on my computer that’s why sharing.
I have VS 2013 Ultimate just downloaded, when I start it, it errors: “The operation could not be completed. No such interface supported”. So in addition, No such interface is supported. And to mention It gives me the error inRussian language for “No such interface is supported”. The first part of the error in English and the second in Russian, why, maybe because I have 2 languages installed, I have tried everything, maybe i should reboot the system after the update? Give me some clues, write to: gennady46@hotmail.com